Description
Cefipime Sulbactam is a formula formed by the combination of cefepime and sulbactam. Cefepime is an antibiotic that prevents the formation of bacterial protective covering, which is essential for the survival of bacteria. Sulbactam is an inhibitor that stops beta-lactamases, beta-lactamases is a bacterial enzymes. These enzymes are responsible for the breakdown of the antibiotic, like cefepime.
Cefipime Sulbactam injection may cause some side effects, such as injection site reactions, like redness and itching. These are the side effects that may not require medical attention, but if they increase, then the patients must consult a professional healthcare specialist.
Working of the Cefipime + Sulbactam
The working of the Cefipime + Sulbactam injection is completely based on the two of its components, that is, Cefipime and Sulbactam. The Cefipime present in it stops the formation of essential protective coverings that are required for the survival of the bacteria in the human body, The covering is responsible for the immunity of the bacteria for the natural antibodies present on our body.
The Sulbactam present in it is required to enhance the activity of cefepime against bacteria and reduce the resistance of the bacteria. Together, Cefipime + Sulbactam injection is a perfect blend to treat the bacterial infection. It prevents the breakdown of the beta-lactamases, which are bacterial enzymes that break down the antibiotics like cefepime. Sulbactam enhances the properties of cefepime to destroy the bacteria that produce beta-lactamases.
The dosage and administration
Cefepime sulbactam injection usually comes in the form of sterile powder and is designed for injection.
Cefipime Sulbactam medicine is administered or inserted into the body either by intravenous infusion or by deep intramuscular injection; in this process, Cefipime + Sulbactam directly enters the bloodstream. And start acting quickly against the infection
Uses if Cefipime + Sulbactam injection
- The primary use of Cefipime + Sulbactam is to manage a variety of serious bacterial infections
- Along with its antibacterial property, it is also used in empirical therapy for febrile neutropenia patients
Side effects of Cefipime + Sulbactam
This medicine shows some common side effects, such as:
- Diarrhea
- Injection site reaction
- Rash
- Nausea
- Headache
- Allergic reaction
- Abdominal pain
- Itching
- Difficulty with swallowing
- Seizures
- Confusion
- Dark urine
- Edema
- Pale or yellowish skin
- Sore throat
- Seizures and Encephalopathy
- Acute Kidney Injury
- Neutropenia and Thrombocytopenia:
Dosage and instructions
- The dosage for different diseases and conditions is prescribed differently; some of them are mentioned below:
- Pneumonia: Treatment of moderate-to-severe pneumonia. The injection is taken for 7-10 days or up to 21 days.
- Febrile Neutropenia: Empiric therapy in febrile neutropenic patients. The injection is taken for 7 days or until neutropenia resolves
- Urinary Tract Infections: Treatment of uncomplicated and complicated urinary tract infections (UTIs), including pyelonephritis. The injection is taken for 7-10 days
- Severe UTIs due to Escherichia coli or Klebsiella pneumonia: The injection is taken for 10 days
- Skin/Skin Structure Infections: Treatment of uncomplicated skin and skin structure infections. The injection is taken for 10 days
- Intra-abdominal Infections: Treatment of complicated intra-abdominal infections; use in combination with metronidazole. The injection is taken for 7-10 days
It is important to get every dose of Cefipime + Sulbactam injection as scheduled. If in case you miss any of the doses, you must consult the healthcare centre for a new dosing schedule.
Miss-dosing and double dossing must be prevented
Drug interaction
This combination can interact with
- Aminoglycosides
- Loop diuretics
- Live vaccines
- Anticoagulants
Precautions and warnings
- Do not receive Cefepime + sulbactam if you are allergic to any of its components.
- Consult the doctor if you are pregnant or breastfeeding.
- Inform the doctor if you have diabetes.
Important instructions while using the Cefepime + sulbactam
- The full course of the medication must be completed. Stopping it early can make the infection reappear and can make the treatment harder
- In case of any bloody stool or abdominal cramps
- In case of an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties, quickly consult with doctors
- If you have a history of gastrointestinal diseases linked to the use of any kind of
antibiotic, this medication must be used cautiously due to the risk of Clostridium difficile-
associated diarrhoe
Storage instruction
- Keep all the medicine away from children and pets
- Keep it in a cool place
- The packaging of the medicine must not be damaged.
- For more storage details, consult the product instructions and the pharmacist